GENÉTICA E AS MUDANÇAS NAS DOENÇAS NEUROLÓGICAS
DOI:
https://doi.org/10.61164/rsv.v2i1.2195Palabras clave:
Avanços; Variantes Genéticas; Biomarcadores Genéticos; Terapia Genética.Resumen
A pesquisa genética das doenças neurológicas tem apresentado avanços significativos nos últimos
10 anos, fornecendo uma compreensão mais aprofundada das bases moleculares e dos fatores que
influenciam essas condições complexas. Estudos genômicos em larga escala têm revelado
variantes genéticas associadas ao risco e biomarcadores genéticos que auxiliam no diagnóstico e
prognóstico das doenças neurológicas, como Alzheimer, Parkinson, Esclerose Lateral Amiotrófica (ELA) e Epilepsia. A terapia genética e a edição de genes têm mostrado promessa no tratamento
dessas doenças, abrindo caminho para abordagens personalizadas e direcionadas. Além disso, a
interação entre fatores genéticos e ambientais tem sido investigada, destacando o papel dos fatores
ambientais na suscetibilidade e progressão das doenças neurológicas. Apesar dos avanços,
desafios permanecem, como a interpretação dos dados genômicos e a tradução dessas
descobertas em tratamentos clínicos eficazes. Perspectivas futuras incluem a medicina genômica
personalizada e a integração de dados genômicos multidimensionais.
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