ASSOCIAÇÃO ENTRE BIOMATERIAIS À BASE DE QUITOSANA E ÓLEOS ESSENCIAIS DE Thymus vulgaris L. E Origanum vulgare L. COMO ALTERNATIVA NO COMBATE A INFECÇÕES ORAIS
DOI:
https://doi.org/10.61164/rmnm.v14i1.2078Palavras-chave:
Fitoterapia, Materiais biocompatíveis, OdontologiaResumo
A caracterização, desenvolvimento e aplicabilidade biomédica de biomateriais à base de quitosana na regeneração de tecidos danificados por doenças e/ou lesões é uma temática crescente entre as pesquisas científicas. A quitosana é um biopolímero linear, derivado da quitina, que apresenta diversas propriedades terapêuticas, ganhando forte destaque para seu potencial antimicrobiano. Além disso, esse biopolímero permite a associação com outras drogas que podem potencializar seus efeitos farmacológicos, a exemplo de óleos essenciais ricos em timol e carvacrol. O presente estudo teve por objetivo verificar na literatura a eficácia da associação entre biomateriais à base de quitosana e óleos essenciais de Thymus vulgaris L. e Origanum vulgare L. como terapêutica alternativa no combate a infecções orais. Trata-se de uma revisão narrativa da literatura, com abordagem documental e observacional. Diversos estudos disponíveis na literatura comprovam que biomateriais à base de quitosana impregnados com óleos essenciais demonstram uma potencialização da atividade antimicrobiana contra diferentes microrganismos. Além de promoverem efeitos sinérgicos quando associados aos biomateriais, os óleos essenciais podem cooperar com biopolímeros durante a fabricação de scaffolds ou membranas. Diante da literatura pré-existente torna-se evidente que a associação entre biomateriais à base de quitosana e produtos de origem natural, a exemplo dos óleos essenciais de Thymus vulgaris L. e Origanum vulgare L., pode constituir uma importante alternativa no tratamento de infecções orais, sendo esta uma opção de baixo custo e acessível.
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